CEM微波合成用于Aspartimide的研究

更新時間：2012-06-29 點擊次數：2540

INTRODUCTION

VIP （vasoactive intestinal peptide）, a peptide hormone, has been implicated in a number of biological processes including: increasing digestive system motility, stimulating pepsinogen secretion, controlling the mammalian circadian timekeeping machinery, regulating prolactin secretion, and causing vasodilation. One problem with synthesis of VIP is aspartimide formation during Fmoc deprotection. Aspartimide formation occurs most frequently in peptides containing Asp followed by Asn（Trt）, Gly, Thr, or Ser. The use of 5% piperazine with 0.1 M HOBt for the deprotection solution can readily reduce the amount of aspartimide formation during microwave peptide synthesis providing the VIP peptide in high crude purity compared to the conventional method.

Figure 1: Aspartimide Formation

Liberty 全自動流動微波多肽合成系統

更多詳情，請培安公司：
：北京：上海：成都：廣州：
: sales@pynnco.com ：www.pynnco.com

上一篇：CEM微波合成用于Racemization的研究
下一篇：Fast Trac快速脂肪分析儀

精品国产自在免费观看_精品国产黑丝Av_日本免费高清不卡_国产成人影亚洲A_五月精品中文字幕,我欲封天 耳根 小说零,豆豆小说阅读网,有声小说

CEM微波合成用于Aspartimide的研究

精品国产自在免费观看_精品国产黑丝Av_日本免费高清不卡_国产成人影亚洲A_五月精品中文字幕,我欲封天耳根小说零,豆豆小说阅读网,有声小说